6Z3R: Structure of SMG1-8-9 kinase complex bound to UPF1-LSQ

PDB ID: 6Z3RDownload
MMDB ID: 189337
PDB Deposition Date: 2020/5/21
Updated in MMDB: 2020/10
Experimental Method:
electron microscopy
Resolution: 2.97  Å
Source Organism:
Similar Structures:
Biological Unit for 6Z3R: tetrameric; determined by author and by software (PISA)
Molecular Components in 6Z3R
Label Count Molecule
Proteins (4 molecules)
1
Serine/threonine-protein Kinase Smg1,serine/threonine-protein Kinase Smg1,smg1,serine/threonine-protein Kinase Smg1,serine/threonine-protein Kinase Smg1,serine/threonine-protein Kinase Smg1
(Gene symbol: SMG1)
Molecule annotation
1
Protein Smg8
(Gene symbol: SMG8)
Molecule annotation
1
Protein Smg9
(Gene symbol: SMG9)
Molecule annotation
1
Regulator of Nonsense Transcripts 1
(Gene symbol: UPF1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
2
1
INOSITOL HEXAKISPHOSPHATEINOSITOL HEXAKISPHOSPHATE
3
1
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
4
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303