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7EA8:
Human SETD2 bound to a nucleosome containing oncohistone mutations
PDB ID:
7EA8
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MMDB ID:
205107
PDB Deposition Date:
2021/3/6
Updated in MMDB:
2021/07
Experimental Method:
electron microscopy
Resolution:
3.1 Å
Source Organism:
synthetic construct
▼
Taxonomy
Molecule
synthetic construct
I, J
Homo sapiens
L, A, B, C, D, E, F, G, H
Similar Structures:
VAST+
Download sequence data
Biological Unit for 7EA8: undecameric; determined by author
Molecular Components in 7EA8
Label
Count
Molecule
Proteins (9 molecules)
L
1
Histone-lysine N-methyltransferase Setd2
A
E
2
Histone H3.3
B
F
2
Histone H4
C
G
2
Histone H2A Type 1-D
D
H
2
Histone H2B Type 2-E
Nucleotides(2 molecules)
I
1
601-dna
J
1
601-dna
Chemicals and Non-standard biopolymers (4 molecules)
1
3
ZINC ION
2
1
S-ADENOSYLMETHIONINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303