7JSN: Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6

PDB ID: 7JSNDownload
MMDB ID: 200530
PDB Deposition Date: 2020/8/15
Updated in MMDB: 2024/06
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 7JSN: hexameric; determined by author
Molecular Components in 7JSN
Label Count Molecule
Proteins (6 molecules)
1
ROD Cgmp-specific 3',5'-cyclic Phosphodiesterase Subunit Alpha
Molecule annotation
1
ROD Cgmp-specific 3',5'-cyclic Phosphodiesterase Subunit Beta
Molecule annotation
2
Guanine Nucleotide-binding Protein G(t) Subunit Alpha-1, Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1 Chimera
(Gene symbol: GNAT1)
Molecule annotation
2
Retinal ROD Rhodopsin-sensitive Cgmp 3',5'-cyclic Phosphodiesterase Subunit Gamma
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
ZINC IONZINC ION
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE
4
2
GUANOSINE-3',5'-MONOPHOSPHATEGUANOSINE-3',5'-MONOPHOSPHATE
5
2
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303