7M3H: Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor

PDB ID: 7M3HDownload
MMDB ID: 220426
PDB Deposition Date: 2021/3/18
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.27  Å
Source Organism:
Similar Structures:
Biological Unit for 7M3H: dimeric; determined by author and by software (PISA)
Molecular Components in 7M3H
Label Count Molecule
Proteins (2 molecules)
2
Hydroxymethylglutaryl-coa Reductase, Degradative
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
5-[(4-butylphenyl)sulfamoyl]-2-hydroxybenzoic acid5-[(4-butylphenyl)sulfamoyl]-2-hydroxybenzoic acid
2
3
SULFATE IONSULFATE ION
3
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303