7M56: Structure of human endothelial nitric oxide synthase heme domain in complex with 7-((3-(3-aminophenethyl)phenoxy)methyl)quinolin-2-amine

PDB ID: 7M56Download
MMDB ID: 213622
PDB Deposition Date: 2021/3/22
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.957  Å
Source Organism:
Similar Structures:
Biological Unit for 7M56: dimeric; determined by author and by software (PISA)
Molecular Components in 7M56
Label Count Molecule
Proteins (2 molecules)
2
Nitric Oxide Synthase, Endothelial
(Gene symbol: NOS3)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
2
5,6,7,8-TETRAHYDROBIOPTERIN5,6,7,8-TETRAHYDROBIOPTERIN
3
3
7-({3-[2-(6-aminopyridin-2-yl)ethyl]phenoxy}methyl)quinolin-2-amine7-({3-[2-(6-aminopyridin-2-yl)ethyl]phenoxy}methyl)quinolin-2-amine
4
3
ACETATE IONACETATE ION
5
2
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
6
1
ZINC IONZINC ION
7
2
GLYCEROLGLYCEROL
8
1
GADOLINIUM ATOMGADOLINIUM ATOM
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303