7NEZ: Structure of topotecan-bound ABCG2

PDB ID: 7NEZDownload
MMDB ID: 201279
PDB Deposition Date: 2021/2/5
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.39  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 7NEZ: hexameric; determined by author and by software (PISA)
Molecular Components in 7NEZ
Label Count Molecule
Proteins (6 molecules)
2
Atp-binding Cassette Sub-family G Member 2
Molecule annotation
2
5d3(fab) Light Chain Variable Domain
Molecule annotation
2
5d3(fab) Heavy Chain Variable Domain
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
(S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE(S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE
2
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303