7NIW: Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab (posaconazole-bound, inward-open conformation)

PDB ID: 7NIWDownload
MMDB ID: 205937
PDB Deposition Date: 2021/2/14
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.8  Å
Source Organism:
Similar Structures:
Biological Unit for 7NIW: trimeric; determined by author
Molecular Components in 7NIW
Label Count Molecule
Proteins (3 molecules)
1
Phosphatidylcholine Translocator Abcb4
(Gene symbol: ABCB4)
Molecule annotation
1
4B1 Fab-fragment Light Chain
Molecule annotation
1
4B1 Fab-fragment Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
6
CHOLESTEROLCHOLESTEROL
2
1
POSACONAZOLEPOSACONAZOLE
3
1
1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303