7OCF: Active state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD)

PDB ID: 7OCFDownload
MMDB ID: 203071
PDB Deposition Date: 2021/4/26
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.6  Å
Source Organism:
Similar Structures:
Biological Unit for 7OCF: octameric; determined by author and by software (PISA)
Molecular Components in 7OCF
Label Count Molecule
Proteins (8 molecules)
2
Isoform Flip of Glutamate Receptor 1
(Gene symbol: Gria1)
Molecule annotation
2
Isoform Flip of Glutamate Receptor 2
(Gene symbol: Gria2)
Molecule annotation
2
Protein Cornichon Homolog 2
(Gene symbol: Cnih2)
Molecule annotation
2
Voltage-dependent Calcium Channel Gamma-8 Subunit
(Gene symbol: Cacng8)
Molecule annotation
Chemicals and Non-standard biopolymers (34 molecules)
1
4
CYCLOTHIAZIDECYCLOTHIAZIDE
2
26
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
3
4
GLUTAMIC ACIDGLUTAMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303