7XVE: Human Nav1.7 mutant class-I

PDB ID: 7XVEDownload
MMDB ID: 219030
PDB Deposition Date: 2022/5/21
Updated in MMDB: 2022/08
Experimental Method:
electron microscopy
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 7XVE: trimeric; determined by author
Molecular Components in 7XVE
Label Count Molecule
Proteins (3 molecules)
1
Sodium Channel Protein Type 9 Subunit Alpha
(Gene symbol: SCN9A)
Molecule annotation
1
Sodium Channel Subunit Beta-1
(Gene symbol: SCN1B)
Molecule annotation
1
Sodium Channel Subunit Beta-2
(Gene symbol: SCN2B)
Molecule annotation
Chemicals and Non-standard biopolymers (42 molecules)
1
11
2-acetamido-2-deoxy-beta-D-glucopyranose (Link to PubChem not yet available)2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
CHOLESTEROL HEMISUCCINATE (Link to PubChem not yet available)CHOLESTEROL HEMISUCCINATE
3
4
CHOLESTEROL (Link to PubChem not yet available)CHOLESTEROL
4
18
1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE (Link to PubChem not yet available)1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE
5
1
(2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate (Link to PubChem not yet available)(2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
6
6
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE (Link to PubChem not yet available)1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
7
1
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine (Link to PubChem not yet available)O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303