7ZSM: human purine nucleoside phosphorylase in complex with JS-375

PDB ID: 7ZSMDownload
MMDB ID: 230213
PDB Deposition Date: 2022/5/7
Updated in MMDB: 2023/06
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 7ZSM: trimeric; determined by author and by software (PISA)
Molecular Components in 7ZSM
Label Count Molecule
Proteins (3 molecules)
3
Purine Nucleoside Phosphorylase
(Gene symbol: PNP)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
3
[(~{E})-2-[4-methoxy-2-[(4-oxidanylidene-3,5-dihydropyrrolo[3,2-d]pyrimidin-7-yl)sulfanyl]phenyl]ethenyl]phosphonic acid[(~{E})-2-[4-methoxy-2-[(4-oxidanylidene-3,5-dihydropyrrolo[3,2-d]pyrimidin-7-yl)sulfanyl]phenyl]ethenyl]phosphonic acid
2
6
SULFATE IONSULFATE ION
3
9
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303