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8BOT:
Cryo-EM structure of NHEJ supercomplex(trimer)
PDB ID:
8BOT
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MMDB ID:
232094
PDB Deposition Date:
2022/11/15
Updated in MMDB:
2023/08
Experimental Method:
electron microscopy
Resolution:
7.76 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Molecular Components in 8BOT
Label
Count
Molecule
Proteins (19 molecules)
K
L
N
O
4
DNA Repair Protein Xrcc4
(Gene symbol:
XRCC4
)
M
P
2
DNA Ligase 4
(Gene symbol:
LIG4
)
Q
R
X
Y
4
Non-homologous End-joining Factor 1
(Gene symbol:
NHEJ1
)
F
A
S
3
DNA-dependent Protein Kinase Catalytic Subunit
G
B
T
3
X-ray Repair Cross-complementing Protein 6
(Gene symbol:
XRCC6
)
H
C
U
3
X-ray Repair Cross-complementing Protein 5
(Gene symbol:
XRCC5
)
Nucleotides(6 molecules)
I
V
2
DNA (28-mer)
J
W
2
DNA (27-mer)
D
1
DNA (24-mer)
E
1
DNA (24-mer)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303