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8OGJ: Structure of Candida albicans 80S ribosome in complex with mefloquine

PDB ID:	8OGJ Download
MMDB ID:	252898
PDB Deposition Date:	2023/3/20
Updated in MMDB:	2024/10
Experimental Method:	electron microscopy
Resolution:	3.1 Å
Source Organism:	Candida albicans
Similar Structures:

Biological Unit for 8OGJ: 79-meric; determined by author

Molecular Components in 8OGJ
Label	Count	Molecule
Proteins (74 molecules)
j	1	60S Ribosomal Protein L2-b
k	1	60S Ribosomal Protein L3
l	1	60S Ribosomal Protein L4-b
m	1	60S Ribosomal Protein L5
n	1	60S Ribosomal Protein L6
o	1	60S Ribosomal Protein L7-a
p	1	60S Ribosomal Protein L8
q	1	60S Ribosomal Protein L9-b
r	1	60S Ribosomal Protein L10
s	1	60S Ribosomal Protein L11-b
t	1	60S Ribosomal Protein L13
u	1	60S Ribosomal Protein L14-b
v	1	60S Ribosomal Protein L15-a
w	1	Ribosomal Protein L13
x	1	Ribosomal Protein L22
y	1	60S Ribosomal Protein L18-a
z	1	60S Ribosomal Protein L19-a
0	1	60S Ribosomal Protein L20
2	1	60S Ribosomal Protein L21-a
5	1	60S Ribosomal Protein L22-b
6	1	60S Ribosomal Protein L23-a
7	1	60S Ribosomal Protein L24-a
8	1	60S Ribosomal Protein L25
9	1	Ribosomal Protein L24
AA	1	60S Ribosomal Protein L27
AB	1	60S Ribosomal Protein L28
AC	1	60S Ribosomal Protein L29
AD	1	60S Ribosomal Protein L30
AE	1	60S Ribosomal Protein L31-b
AF	1	60S Ribosomal Protein L32
AG	1	60S Ribosomal Protein L33-a
AH	1	60S Ribosomal Protein L34-b
AI	1	Ribosomal Protein L29
AJ	1	60S Ribosomal Protein L36
AK	1	60S Ribosomal Protein L37-b
AL	1	60S Ribosomal Protein L38
AM	1	60S Ribosomal Protein L39
AN	1	60S Ribosomal Protein L40-b
AO	1	60S Ribosomal Protein L41
AP	1	60S Ribosomal Protein L42-b
AQ	1	60S Ribosomal Protein L43-a
B	1	40S Ribosomal Protein S0
C	1	40S Ribosomal Protein S1
D	1	Ribosomal Protein S5
E	1	Ribosomal Protein S3
F	1	40S Ribosomal Protein S4
G	1	Ribosomal Protein S7
H	1	40S Ribosomal Protein S6
I	1	40S Ribosomal Protein S7
J	1	40S Ribosomal Protein S8
K	1	Ribosomal Protein S4
L	1	40S Ribosomal Protein S10-a
M	1	40S Ribosomal Protein S11a
N	1	40S Ribosomal Protein S12
O	1	40S Ribosomal Protein S13
P	1	40S Ribosomal Protein S14-a
Q	1	40S Ribosomal Protein S15
R	1	40S Ribosomal Protein S16
S	1	40S Ribosomal Protein S17-b
T	1	40S Ribosomal Protein S18-b
U	1	40S Ribosomal Protein S19-a
V	1	Ribosomal Protein S10
W	1	40S Ribosomal Protein S21
X	1	40S Ribosomal Protein S22-a
Y	1	Ribosomal Protein S23 (S12)
Z	1	40S Ribosomal Protein S24
a	1	40S Ribosomal Protein S25
b	1	40S Ribosomal Protein S26
c	1	40S Ribosomal Protein S27
d	1	40S Ribosomal Protein S28-b
e	1	40S Ribosomal Protein S29a
f	1	40S Ribosomal Protein S30
g	1	Ubiquitin-40s Ribosomal Protein S31 Fusion Protein
h	1	Guanine Nucleotide-binding Protein Subunit Beta-like Protein
Nucleotides(5 molecules)
1	1	25S Ribosomal RNA
3	1	5S Ribosomal RNA
4	1	5.8s Ribosomal RNA
10	1	Mixture of Endogenous E-trnas
A	1	18S Ribosomal RNA
Chemicals and Non-standard biopolymers (441 molecules)
1	2	Mefloquine
2	1	SPERMINE (FULLY PROTONATED FORM)
3	432	MAGNESIUM ION
4	6	ZINC ION

* Click molecule labels to explore molecular sequence information.

Citing MMDB

Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303