8SJ2: Structure of ternary complex of cGAS with dsDNA and bound ATP and 2'-dGTP

PDB ID: 8SJ2Download
MMDB ID: 245870
PDB Deposition Date: 2023/4/17
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 2.23  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8SJ2: hexameric; determined by author
Molecular Components in 8SJ2
Label Count Molecule
Proteins (2 molecules)
2
Cyclic Gmp-amp Synthase
Molecule annotation
Nucleotides(4 molecules)
4
Palindromic Dna18
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
2
2
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE
3
2
MAGNESIUM IONMAGNESIUM ION
4
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303