Table 2.

Features of Juvenile Hemochromatosis

FeatureHJV Hemochromatosis: % of Persons w/FeatureHAMP Hemochromatosis: Proportion of Persons w/Feature 1
Cardiomyopathy35%-37%4/7
Hypogonadotropic hypogonadism67%-91%See footnote 2.
Reduced glucose intolerance / diabetes30%-57%7/8
Liver fibrosis44%-58% 36/7 4
Liver cirrhosis27%-42%
Hyperpigmentation24.5%See footnote 2.
1.

In HAMP hemochromatosis data are limited and clinical descriptions have been incomplete although similar to HJV hemochromatosis.

2.

Not enough information is available to determine the proportion of individuals with this feature.

3.

Not all individuals in reported studies underwent liver biopsy.

4.

Proportion of persons with HAMP hemochromatosis with either liver fibrosis or cirrhosis

From: Juvenile Hemochromatosis

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