Table 2. [FLNA Deficiency: Frequency of Select Features (Males and Females)]. - GeneReviews®

Feature	% of Persons w/Feature	Comment
Seizure disorder	75%-90%
Cardiovascular	65%	Patent ductus arteriosus; dilatation & rupture of thoracic aorta; atrial & ventricular septal defects; valvular dystrophy; vasculopathy &/or coagulopathy → stroke
Pulmonary disease	25%	Pulmonary hypertension, alveolar hypoplasia, emphysema, asthma, chronic bronchitis
↓ gastric motility	6%	Chronic intestinal pseudo-obstruction, feeding difficulties
Joint hypermobility	<15%
Distally shortened digits	<5%

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