Table 1.

The FDA Allopurinol Dosage and Administration (2019)

DrugDosage
AllopurinolThe minimal effective dosage is 100–200 mg daily and the maximal recommended dosage is 800 mg daily. To reduce the possibility of gout flares, it is recommended that the individual start with a low dose of allopurinol tablets (100 mg daily) and increase at weekly intervals by 100 mg until a serum uric acid level of 6 mg/dL or less is attained but without exceeding the maximal recommended dosage.

This FDA table is adapted from (1). Dosage information given is for individuals with normal renal function.

From: Allopurinol Therapy and HLA-B*58:01 Genotype

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