Table 8.

Recommended Brain MRI Schedule for Early Detection of Childhood Cerebral Adrenoleukodystrophy (cCALD) Abnormalities in At-Risk Males

AgeIntervalType of Brain MRIComment
12 mos - 3 yrsYearlyStandard T1/T2-weighted sequencesUse of general anesthesia is advisable until the boy can lie still.
3-12 yrsEvery 6 mosStandard T1/T2-weighted sequences w/contrast
>12 yrsYearlyStandard T1/T2-weighted sequencesRepeat yearly; some males develop cerebral changes in adulthood.

cCALD = childhood cerebral adrenoleukodystrophy

From: X-Linked Adrenoleukodystrophy

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