Table 8, PICOT specifications for Future Research Need #4 - Treatment of Hepatitis C Virus Infection in Adults: Future Research Needs

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Table 8PICOT specifications for Future Research Need #4

Example Research Question(s)	Proposed Study Design(s)	P	I	C	O	T
How does the efficacy of antiviral treatment for HCV differ in patients identified through screening vs. those identified based on symptoms or abnormal liver tests?	RCT or cohort.	Individuals with HCV.	Antiviral regimens.	Screen-detected vs. symptomatic individuals with HCV or those with elevated liver function tests.	Clinical and intermediate outcomes.	Long-term followup.

: Note: HCV=hepatitis C virus, PICOT= Population, Intervention, Comparator, Outcome, and Timing, RCT=randomized controlled trial.

From: Results

Cover of Treatment of Hepatitis C Virus Infection in Adults: Future Research Needs

Treatment of Hepatitis C Virus Infection in Adults: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 76 [Internet].

Future Research Needs Papers, No. 28.

Chou R, Bougatsos C, Blazina I, et al.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2013 Jan.

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