Table 4Relative risks of clear/nearly clear on IAGI/PGA for all interventions compared to twice daily vehicle/placebo – Sensitvity analysis wherein all data and twice daily combined vitamin D analogue and potent corticosteroid are included

InterventionMedian RRLower Credible IntervalUpper Credible IntervalProbability most effective in SAProbability most effective in base case
Combined vitamin D and potent corticosteroid BD5.9154.8206.56745.6NA
Very potent corticosteroid BD5.7364.4686.54929.048.0
Combined vitamin D and potent corticosteroid OD5.2063.6676.2493.212.7
Very potent corticosteroid OD4.9611.5266.81618.725.3
Potent corticosteroid BD4.7163.4645.7360.32.1
Concurrent vitamin D and potent corticosteroid4.6912.6776.1692.97.9
Vitamin D or vitamin D analogue BD3.8452.8454.7890.00.0
Potent corticosteroid OD3.5601.5845.5370.10.2
Vitamin D or vitamin D analogue OD3.2131.6554.9880.00.0
Dithranol OD3.0181.5514.7510.00.1
Coal Tar BD2.9211.3034.8950.03.6
Tazarotene OD2.0080.4594.9360.10.2
Coal Tar OD0.8520.1033.6170.00.0
Placebo OD0.7290.2291.9100.00.0

From: Appendix K, Network meta-analysis topicals trunk and limbs

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Psoriasis: Assessment and Management of Psoriasis.
NICE Clinical Guidelines, No. 153.
National Clinical Guideline Centre (UK).
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