Table 105Evidence profile comparing tar oil plus sub-erythemogenic BBUVB vs placebo plus maximally erythemogenic BBUVB

Quality assessmentNo of patientsEffectQuality
No of studiesDesignRisk of biasInconsistencyIndirectnessImprecisionOther considerationsTar oil + low dose BBUVBPlacebo + high dose BBUVBRelative (95% CI)Absolute
Clearance (follow-up 12 weeks)
1
Menkes 1985
randomised trialsvery seriousano serious inconsistencyseriousbvery seriouscnone19/30 (63.3%)14/19 (73.7%)RR 0.86 (0.59 to 1.26)103 fewer per 1000 (from 302 fewer to 192 more)⊕○○○
VERY LOW
Mean number of treatments to clear (follow-up 12 weeks; Better indicated by lower values)
1
Menkes 1985
randomised trialsvery seriousano serious inconsistencyseriousbseriousdnone1914-MD 4
Tar: 17
Placebo: 21
P<0.05
⊕○○○
VERY LOW
a

No allocation concealment, unblended

b

Groups received different doses of UVB

c

Confidence interval crosses the boundary for clinical significance in favour of both interventions, as well as line of no effect

d

No measure of variance reported

From: 9, Phototherapy

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