Table 118Relative risk of SCC in PUVA patients compared with the general population

StudyStandardised morbidity ratio
Population ratesPerson counts
STERN1984AAll incident tumours after ≥22 months
16.2 (13.0–19.9)
All incident tumours after ≥22 months
9.3 (6.9–12.2)
STERN1988AFirst tumour after ≥58 months
9.5 (7.2–12.3)

All incident tumours after ≥58 months
11.4 (9.1–14.2)
STERN199427.0 (24.2–30.1)11.9 (10.1–14.0)
STERN1998AFirst cancer after 1985(a)
17.6 (15.6–19.8)
Genital tumours
STERN1990Total count
Invasive: 95.7 (43.8–181.8)
STERN2002After May 1989(b)
Invasive: 87.7 (42.1–161.3)
Invasive + in situ: 89.4 (51.1–145.2)

Total follow-up
Invasive: 134.6 (89.5–194.6)
After May 1989(b)
Invasive: 52.6 (19.3–114.6)
Invasive + in situ: 61.5 (30.7–110.0)

Total follow-up
Invasive: 81.7 (52.1–122.6)
a

The rate after 1985 was an arbitrary time-point chosen to investigate whether the risk changed at longer follow-up points

b

The rate after 1989 was reported to capture the incidence since the last date of surveillance for the 1990 report

From: 9, Phototherapy

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Psoriasis: Assessment and Management of Psoriasis.
NICE Clinical Guidelines, No. 153.
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