Table 5.

Activity Status of Selected CYP3A4 Alleles

Allele typeCYP3A4 alleles
Normal function *1A
Decreased function *16A, *16B, *22
No function *6, *20, *26

For a comprehensive list of CYP3A4 alleles, please see PharmVar.

From: Clozapine Therapy and CYP Genotype

Cover of Medical Genetics Summaries
Medical Genetics Summaries [Internet].
Pratt VM, Scott SA, Pirmohamed M, et al., editors.
Copyright Notice

All Medical Genetics Summaries content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license which permits copying, distribution, and adaptation of the work, provided the original work is properly cited and any changes from the original work are properly indicated. Any altered, transformed, or adapted form of the work may only be distributed under the same or similar license to this one.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.