Table 11.1.3, Comparison of Results for Direct and Indirect Analysis of Mortality - Neutropenic Sepsis: Prevention and Management of Neutropenic Sepsis in Cancer Patients

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Indirect comparisons in the upper triangle, direct comparisons in the lower triangle.

Indirect comparision Direct comparison	carbapenem	Uridipenicillin	3G cef	4G cef	Uridipenicillin + aminoglycoside	3G cef + aminoglycoside	4G cef + aminoglycoside
carbapenem	@@@@	1.75	1.19	0.85	0.97	0.93	0.79
	@@@@	1.14 to 2.63	0.84 to 1.61	0.6 to 1.23	0.71 to 1.3	0.65 to 1.33	0.39 to 1.85
uridipenicillin	0.4	@@@@	0.67	0.49	0.55	0.53	0.45
	0.115 to 1.388	@@@@	0.44 to 1.1	0.32 to 0.78	0.37 to 0.83	0.34 to 0.88	0.2 to 1.23
3G cef	0.997	1.178	@@@@@	0.71	0.82	0.8	0.68
	0.597 to 1.664	0.072 to 19.167	@@@@@	0.51 to 1.08	0.59 to 1.11	0.54 to 1.12	0.32 to 1.61
4G cef	1.368	1.56	1.558	@@@@	1.14	1.12	0.93
	0.714 to 2.624	0.73 to 3.33	0.937 to 2.589	@@@@	0.75 to 1.69	0.68 to 1.64	0.47 to 2.08
uridipenicillin+aminoglcoside	1.004	1.488	1.247		@@@@@	0.98	0.83
	0.565 to 1.786	0.859 to 2.576	0.903 to 1.722		@@@@@	0.65 to 1.43	0.39 to 2.04
3G cef + aminoglycoside	1.065	2.155	1.204	0.593		@@@@	0.85
	0.691 to 1.641	0.871 to 5.333	0.685 to 2.118	0.07 to 4.996		@@@@	0.4 to 2.13
4G cef + aminoglycoside				1.696			@@@@@
				0.154 to 18.673			@@@@@

Neutropenic Sepsis: Prevention and Management of Neutropenic Sepsis in Cancer Patients.

NICE Clinical Guidelines, No. 151.

National Collaborating Centre for Cancer (UK).

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