From: Childhood Cancer Genomics (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 2. Characteristics of Melanocytic Lesions
| Tumor | Affected Gene |
|---|---|
| Melanoma | BRAF, NRAS, KIT, NF1 |
| Spitzoid melanoma | Kinase fusions (RET, ROS, MET, ALK, BRAF, NTRK1) |
| Spitz nevus | HRAS; BRAF and NRAS (uncommon) |
| Acquired nevus | BRAF |
| Dysplastic nevus | BRAF, NRAS |
| Blue nevus | GNAQ |
| Ocular melanoma | GNAQ |
| Congenital nevi | NRAS |