From: Childhood Cancer Genomics (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 7. Frequency of Gene Alterations in Patients With Fusion-Negative (FN) and Fusion-Positive (FP) Rhabdomyosarcomaa
| Gene | % FN Cases With Gene Alteration | % FP Cases With Gene Alteration |
|---|---|---|
| NRAS | 17% | 1% |
| KRAS | 9% | 1% |
| HRAS | 8% | 2% |
| FGFR4 | 13% | 0% |
| NF1 | 15% | 4% |
| BCOR | 15% | 6% |
| TP53 | 13% | 4% |
| CTNNB1 | 6% | 0% |
| CDK4 | 0% | 13% |
| MYCN | 0% | 10% |
aAdapted from Shern et al.[50]