Table 5SVR12 in treatment-naïve patients treated with glecaprevir + pibrentasvir, arranged by genotype

Number of studiesNumber of armsTotal NPooled proportion (95% CI)GRADE
Genotype 1Trial evidence
All evidence
Genotype 2Trial evidence
All evidence
Genotype 3Trial evidence
SURVEYOR-II65,118
ENDURANCE-360
234190.95 (0.93, 0.97)⊕⊕⊕⊕
All evidenceSame as trial-only evidence
Genotype 4Trial evidence
All evidence
Genotype 5Trial evidence
All evidence
Genotype 6Trial evidence
All evidence
Mixed genotypeTrial evidence
All evidence

From: Web Annex 3.2, Adult hepatitis C virus treatment systematic review; supporting evidence

Cover of Guidelines for the Care and Treatment of Persons Diagnosed with Chronic Hepatitis C Virus Infection
Guidelines for the Care and Treatment of Persons Diagnosed with Chronic Hepatitis C Virus Infection [Internet].
Geneva: World Health Organization; 2018 Jul.
© World Health Organization 2018.

Sales, rights and licensing. To purchase WHO publications, see http://apps.who.int/bookorders. To submit requests for commercial use and queries on rights and licensing, see http://www.who.int/about/licensing.

Third-party materials. If you wish to reuse material from this work that is attributed to a third party, such as tables, figures or images, it is your responsibility to determine whether permission is needed for that reuse and to obtain permission from the copyright holder. The risk of claims resulting from infringement of any third-party-owned component in the work rests solely with the user.

Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO license (CC BY-NC-SA 3.0 IGO; https://creativecommons.org/licenses/by-nc-sa/3.0/igo).

Under the terms of this license, you may copy, redistribute and adapt the work for non-commercial purposes, provided the work is appropriately cited, as indicated below. In any use of this work, there should be no suggestion that WHO endorses any specific organization, products or services. The use of the WHO logo is not permitted. If you adapt the work, then you must license your work under the same or equivalent Creative Commons license. If you create a translation of this work, you should add the following disclaimer along with the suggested citation: “This translation was not created by the World Health Organization (WHO). WHO is not responsible for the content or accuracy of this translation. The original English edition shall be the binding and authentic edition”.

Any mediation relating to disputes arising under the license shall be conducted in accordance with the mediation rules of the World Intellectual Property Organization.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.