Table 15Prostacyclin-Like Adverse Events in GRIPHON by Titration and Maintenance Dosing Phases

SelexipagPlacebo
Adverse event, n (%)Titration N = 509Maintenance N = 509Titration N = 508Maintenance N = 508
Headache▬▬▬▬
Diarrhea▬▬▬▬
Nausea▬▬▬▬
Pain in jaw▬▬▬▬
Myalgia▬▬▬▬
Pain in extremity▬▬▬▬
Vomiting▬▬▬▬
Flushing▬▬▬▬
Dizziness▬▬▬▬
Arthralgia▬▬▬▬
Musculoskeletal pain▬▬▬▬
Temporomandibular joint syndrome▬▬▬▬

Source: Clinical Study Report.8

From: 3, Results

Cover of Clinical Review Report: Slexipag (Uptravi)
Clinical Review Report: Slexipag (Uptravi) [Internet].
Copyright © 2017 Canadian Agency for Drugs and Technologies in Health.

The copyright and other intellectual property rights in this document are owned by CADTH and its licensors. These rights are protected by the Canadian Copyright Act and other national and international laws and agreements. Users are permitted to make copies of this document for non-commercial purposes only, provided it is not modified when reproduced and appropriate credit is given to CADTH and its licensors.

Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.