Table 16GRADE findings for association of sporadic accelerationsa and perinatal mortality

Quality assessmentStage of labourNumber of babies with defined FHR patternsNumber (percentage) of babies who diedQuality
Number of studiesDesignRisk of biasInconsistencyIndirectnessImprecision
Sporadic accelerationsa (3 or more accelerations per 30-minute tracing) (women with no identified risk factors for adverse outcome)

1 study

(Krebs 1982)

CohortSerious1,2,3No serious inconsistencySerious4No serious imprecisionFirst 30 minutes of tracing811n = 2 (0.2%)Low
Sporadic accelerationsa (fewer than 3 accelerations per 30-minute tracing) (women with identified risk factors for adverse outcome)

1 study

(Krebs 1982)

CohortSerious1,2,3No serious inconsistencySerious4No serious imprecisionFirst 30 minutes of tracing122n = 12 (9.8%)Very low
Sporadic accelerationsa (3 or more accelerations per 30-minute tracing) (women with identified risk factors for adverse outcome)

1 study

(Krebs 1982)

CohortSerious1,2,3No serious inconsistencySerious4No serious imprecisionFirst 30 minutes of tracing955n = 4 (0.4%)Very low
Sporadic accelerationsa (fewer than 3 accelerations per 30-minute tracing) (women with no identified risk factors for adverse outcome)

1 study

(Krebs 1982)

CohortSerious1,2,3No serious inconsistencySerious4No serious imprecisionFirst 30 minutes of tracing108n = 3 (2.8%)Very low

FHR fetal heart rate

a

Sporadic accelerations occur independently from uterine contractions

1

No exclusion criteria specified hence high risk of selection bias

2

Women’s demographic characteristics not reported

3

Unbalanced cohort; only 4% of adverse outcomes

4

High-risk population

From: Appendix I, GRADE tables

Cover of Addendum to intrapartum care: care for healthy women and babies
Addendum to intrapartum care: care for healthy women and babies.
Clinical Guideline, No. 190.1.
National Guideline Alliance (UK).
Copyright © National Institute for Health and Care Excellence 2017.

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