Table 47GRADE findings for comparison of reducing or stopping oxytocin and not reducing or stopping oxytocin in the presence of an abnormal fetal heart rate tracing

Quality assessmentNumber of women or babiesEffectQuality
Number of studiesDesignRisk of biasInconsistencyIndirectnessImprecisionOther considerationsReducing or stopping oxytocinNot reducing or stopping oxytocinRelative (95% CI)Absolute (95% CI) and p-value (if reported)
Neonatal intensive care unit admission

1 study

(Clark 2015)

Prospective nonrandomised comparative studySerious1No serious inconsistencySerious2Serious3None

91/2364

(3.8%)

276/5272

(5.2%)

RR 0.74 (0.58 to 0.93)14 fewer per 1000 (from 4 fewer to 22 fewer)Very low
Primary caesarean section

1 study

(Clark 2015)

Prospective nonrandomised comparative studySerious1No serious inconsistencySerious2No serious imprecisionNone

630/2364

(26.6%)

923/5272

(17.5%)

RR 1.52 (1.39 to 1.66)91 more per 1000 (from 68 more to 116 more)Very low

CI confidence interval, RR relative risk

1

No adjustments made for potential confounders

2

All women underwent induced labour

3

95% CI crosses 0.75

From: Appendix I, GRADE tables

Cover of Addendum to intrapartum care: care for healthy women and babies
Addendum to intrapartum care: care for healthy women and babies.
Clinical Guideline, No. 190.1.
National Guideline Alliance (UK).
Copyright © National Institute for Health and Care Excellence 2017.

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