Table 15Clinical evidence summary: People with mild cognitive impairment vs control

OutcomesNo of Participants (studies) Follow upQuality of the evidence (GRADE)Relative effect (95 % CI)Anticipated absolute effects
Risk with ControlRisk difference with Mild cognitive impairment (95% CI)
AHI

86

(1 study)

⊕⊝⊝⊝

VERY LOW1,2

due to risk of bias, imprecision

The mean AHI in control group was

12.6

The mean ahi in the intervention groups was

2.3 higher

(3.2 lower to 7.8 higher)

1

Risk of bias was assessed using the QUIPS checklist. Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias

2

Downgraded by 1 increment if the confidence interval crossed one MID or by 2 increments if the confidence interval crossed both MIDs. Default MID (0.5XSD) used to assess imprecision.

From: When to suspect OSAHS, OHS and COPD–OSAHS overlap syndrome

Cover of When to suspect OSAHS, OHS and COPD–OSAHS overlap syndrome
When to suspect OSAHS, OHS and COPD–OSAHS overlap syndrome: Obstructive sleep apnoea/hypopnoea syndrome and obesity hypoventilation syndrome in over 16s: Evidence review A.
NICE Guideline, No. 202.
National Guideline Centre (UK).
Copyright © NICE 2021.

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