Table 7Clinical evidence summary: People with hypertension (essential hypertension) vs control

OutcomesNo of Participants (studies) Follow upQuality of the evidence (GRADE)Relative effect (95 % CI)Anticipated absolute effects
Risk with ControlRisk difference with Hypertensives (95% CI)
apnoea index

80

(1 study)

⊕⊝⊝⊝

VERY LOW

due to risk of bias1

The mean apnoea index in the control groups was 3.3

The mean apnoea index in the intervention groups was

6.7 higher

(5.99 to 7.41 higher)

hypopnoea index

80

(1 study)

⊕⊝⊝⊝

VERY LOW

due to risk of bias1

The mean hypopnoea index in the control groups was 5.6

The mean hypopnoea index in the intervention groups was

2.5 higher

(1.95 to 3.05 higher)

1

Risk of bias was assessed using the QUIPS checklist. Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias

From: When to suspect OSAHS, OHS and COPD–OSAHS overlap syndrome

Cover of When to suspect OSAHS, OHS and COPD–OSAHS overlap syndrome
When to suspect OSAHS, OHS and COPD–OSAHS overlap syndrome: Obstructive sleep apnoea/hypopnoea syndrome and obesity hypoventilation syndrome in over 16s: Evidence review A.
NICE Guideline, No. 202.
National Guideline Centre (UK).
Copyright © NICE 2021.

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