| Outcomes | No of Participants (studies) Follow up | Quality of the evidence (GRADE) | Relative effect (95 % CI) | Anticipated absolute effects | |
|---|---|---|---|---|---|
| Risk with Control | Risk difference with Educational interventions + CPAP versus usual care + CPAP (95% CI) | ||||
|
CPAP Device Usage (hours/night) Higher is better |
1128 (10 studies) |
⊕⊝⊝⊝ due to risk of bias, inconsistency, imprecision, indirectness |
The mean CPAP device usage (hours/night) in the control group was 3.5 |
The mean CPAP device usage (hours/night) in the intervention groups was 0.88 higher (0.4 to 1.36 higher) | |
|
N deemed adherent (≥ four hours/night) Higher is better |
1019 (7 studies) |
⊕⊕⊝⊝ due to risk of bias, imprecision, indirectness | RR 1.31 (1.15 to 1.48) | Moderate | |
| 547 per 1000 |
170 more per 1000 (from 82 more to 263 more) | ||||
| Withdrawal |
1745 (9 studies) |
⊕⊕⊝⊝ due to risk of bias, indirectness | RR 0.73 (0.52 to 1.02) | Moderate | |
| 150 per 1000 |
41 fewer per 1000 (from 72 fewer to 3 more) | ||||
|
Epworth Sleepiness Scale - Comparison of Values at Endpoint- Scale from 0-24 Higher is worse |
355 (3 studies) |
⊕⊝⊝⊝ due to risk of bias, imprecision, indirectness | The mean ESS in the control group was 6.41 |
The mean epworth sleepiness scale scores in the intervention groups was 0.08 lower* (0.92 lower to 0.76 higher) | |
| Mortality (critical outcome) | - | - | - | - | Not reported |
Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias
Downgraded by 1 or 2 increments for heterogeneity, unexplained by subgroup analysis. Random effect analysis used.
Downgraded by one increment if the confidence interval crossed one MID and downgraded by two increments if the confidence interval crossed both MIDs. MID for machine usage (adherence)- 1 hour; Established MIDs for SF-36 physical/mental- 2/3 ; FOSQ- 2 ; ESS −2.5;SAQLI – 2. GRADE default MID (0.5XSD) used for all other continuous outcomes.
Downgraded by 1 or 2 increments because the majority of the evidence included an indirect or very indirect population respectively
Not sleepy in both groups
From: Adherence
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