Table 11Summary of the protocol (PICO table)

PopulationAdults (18 or over) with invasive breast cancer but no distant metastases (M0) treated with breast conserving surgery or mastectomy (including modified radical mastectomy).
InterventionRadiotherapy to internal mammary nodes (± other nodes)
ComparisonNo internal mammary node radiotherapy (± other nodes)
OutcomeCritical
  • Locoregional recurrence rate
  • Disease-free survival
  • Treatment-related morbidity
Important
  • Overall survival
  • HRQoL

HRQoL, health-related quality of lfie; M0, no distant metasases

From: Evidence reviews for breast radiotherapy

Cover of Evidence reviews for breast radiotherapy
Evidence reviews for breast radiotherapy: Early and locally advanced breast cancer: diagnosis and management: Evidence review H.
NICE Guideline, No. 101.
National Guideline Alliance (UK).
Copyright © NICE 2018.

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