| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | No of Participants (studies) | Quality of the evidence (GRADE) | |
|---|---|---|---|---|---|
| Assumed risk | Corresponding risk | ||||
| Free Breathing | Deep Inspiration Breath-Hold | ||||
| Mean Heart Dose at RT (Gy) |
The mean heart dose at RT in the control groups was 2.4 Gy |
The mean mean heart dose at RT in the intervention groups was 1.29 lower (1.81 to 0.77 lower) | - |
236 | Very low5,6,7 |
|
Target Coverage at RT Scale from: 0 to 100. |
The mean target coverage at RT in the control groups was 86.3 % |
The mean target coverage at RT in the intervention groups was 0.5 higher (4.6 lower to 5.6 higher) | - |
81 (1 study1) | Very low7 |
CI: confidence interval; Gy: gray: RT: radiotherapy
Downgraded by 2 levels for very serious inconsistency as I square=89%
Downgraded by 1 level for indirectness due to inclusion of women with only larger breast volumes (estimated volume>750cm3)
Downgraded by 1 level for serious imprecision, as number of events <400
From: Evidence reviews for breast radiotherapy
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