Table 4, Summary clinical evidence profile: Comparison 2. Deep inspiration breathhold versus prone radiotherapy - Evidence reviews for breast radiotherapy

Warning: The NCBI web site requires JavaScript to function. more...

Outcomes	Illustrative comparative risks* (95% CI)	Relative effect (95% CI)	No of Participants (studies)	Quality of the evidence (GRADE)
Mean Heart Dose at RT (Gy)	The mean heart NTD dose at RT in the control groups was 0.66 Gy	The mean heart dose at RT in the intervention groups was 0.22 lower (0.30 to 0.14 lower)	-	28 (1 study¹)	Low²^,³

Outcomes

Illustrative comparative risks* (95% CI)

Relative effect (95% CI)

No of Participants (studies)

Quality of the evidence (GRADE)

Assumed risk

Corresponding risk

Prone RT

Deep Inspiration Breath-Hold

Mean Heart Dose at RT (Gy)

The mean heart NTD dose at RT in the control groups was

0.66 Gy

The mean heart dose at RT in the intervention groups was

0.22 lower

(0.30 to 0.14 lower)

(1 study¹)

Low²^,³

: CI: Confidence interval; Gy: Gray; NTD: normalized total dose; RT: Radiotherapy;
1: Barlett 2015
2: Downgraded by 1 level for serious indirectness as only women with larger breasts included
3: Downgraded by 1 level for serious imprecision, as number of events <400

Evidence reviews for breast radiotherapy: Early and locally advanced breast cancer: diagnosis and management: Evidence review H.

NICE Guideline, No. 101.

National Guideline Alliance (UK).

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.