[Table], Table 7. Chronic Graft-Versus-Host Disease (GVHD) Symptoms in the Mouth and GI Tracta - PDQ Cancer Information Summaries - NCBI Bookshelf

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Table 7. Chronic Graft-Versus-Host Disease (GVHD) Symptoms in the Mouth and GI Tract^a

Organ or Site	Diagnostic^b	Distinctive^c	Other Features^d	Common (Seen With Both Acute and Chronic GVHD)
Mouth	Lichen-type features	Xerostomia		Gingivitis
	Hyperkeratotic plaques	Mucocele		Mucositis
	Restriction of mouth opening from sclerosis	Pseudomembranes^e		Erythema
		Mucosal atrophy		Pain
		Ulcers^e		Pain

GI Tract	Esophageal web		Exocrine pancreatic insufficiency	Anorexia
	Strictures or stenosis in the upper to mid third of the esophagus^e			Nausea
				Vomiting
				Diarrhea
				Weight loss
				Failure to thrive (infants and children)
				Total bilirubin, alkaline phosphatase >2 × ULN^e
				ALT or AST >2 × ULN^e

: ALT = alanine aminotransferase; AST = aspartate aminotransferase; GI = gastrointestinal; ULN = upper limit of normal.
: ^a–eSee definitions in Table 6.

From: Complications, Graft-Versus-Host Disease, and Late Effects After Pediatric Hematopoietic Stem Cell Transplant (PDQ®)

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