Table 16Research recommendation rationale

Research questionWhat is the effectiveness and cost effectiveness of selective dorsal rhizotomy compared to continuous intrathecal baclofen pump to reduce spasticity in adults with cerebral palsy?
Importance to ‘patients’ or the population

Minimise further surgery

Minimise follow up

Reduce complications

Relevance to NICE guidanceAbility to make firm recommendations according to functional level
Relevance to the NHS

Reduce costs of ongoing ITB therapy

Reduce costs of further surgery

National priorities

Ensure equal access to treatments

Reduce variations in treatment practice

Ensure validity of SDR in adult population

Current evidence baseCurrent evidence not available or not applicable to adult population
EqualityApplies to all patients with cerebral palsy and spasticity regardless of functional (GMFCS) level

From: Management of abnormal muscle tone: neurosurgical procedures to reduce spasticity

Cover of Management of abnormal muscle tone: neurosurgical procedures to reduce spasticity
Management of abnormal muscle tone: neurosurgical procedures to reduce spasticity: Cerebral palsy in adults: Evidence review A2.
NICE Guideline, No. 119.
National Guideline Alliance (UK).
Copyright © NICE 2019.

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