Table 23Summary of included studies for inpatient versus outpatient subgroup analysis for comparison 3f Acupuncture + antidepressants versus antidepressants

StudyPopulationInterventionComparisonComments
Inpatient setting (K=2, N=119)

Wang 2014a

RCT

China

Inpatient

N=77

Baseline severity: More severe

Mean age (years): NR

Sex (% female): 72

Ethnicity (% BME): NR

Traditional acupuncture (30 sessions) + any SSRI (dose NR)Any SSRI (dose NR)

Treatment duration (weeks): 6

Outcome (for inpatient versus outpatient subgroup analysis):

  • Depression symptoms change score

Zhang 2007a

RCT

China

Inpatient

N=42

Baseline severity: More severe

Mean age (years): 36.8

Sex (% female): 50

Ethnicity (% BME): NR

Electroacupunctu re (36x 30-min sessions) + paroxetine 10-40mg/dayParoxetine 10-40mg/day

Treatment duration (weeks): 6

Outcome (for inpatient versus outpatient subgroup analysis):

  • Depression symptoms change score

Outpatient setting (K=2, N=637)

Qu 2013

RCT

China

Outpatient

N=160

Baseline severity: More severe

Mean age (years): 33.3

Sex (% female): 59

Ethnicity (% BME): NR

Traditional acupuncture or electroacupuncture (18 sessions) + paroxetine 20-40mg/dayParoxetine 20-40mg/day

Treatment duration (weeks): 6

Outcome (for inpatient versus outpatient subgroup analysis):

  • Depression symptoms change score

Zhao 2019a

RCT

China

Outpatient

N=477

Baseline severity: More severe

Mean age (years): 41.5

Sex (% female): 65

Ethnicity (% BME): NR

Traditional acupuncture or electroacupuncture (18x 30-min sessions) + any SSRI (most commonly paroxetine 20mg/day)Any SSRI (most commonly paroxetine 20mg/day)

Treatment duration (weeks): 6

Outcome (for inpatient versus outpatient subgroup analysis):

  • Depression symptoms change score

BME: black, minority, ethnic; mg: milligrams; N: number of participants; NR: not reported; RCT: randomised controlled trial; SSRI: selective serotonin reuptake inhibitor.

From: Service delivery Models and settings for delivery of services

Cover of Service delivery Models and settings for delivery of services
Service delivery Models and settings for delivery of services: Depression in adults: Evidence review A.
NICE Guideline, No. 222.
Copyright © NICE 2022.

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