Table 5, Summary of included studies for Comparison 4: Stepped care versus standard care for relapse prevention - Service delivery Models and settings for delivery of services

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Study	Population	Intervention	Comparison	Comments
Apil 2012 RCT Netherlands	N=136 Baseline severity: Less severe Mean age (years): 65.6 Sex (% female): 72 Ethnicity (% BME): NR	Stepped care relapse prevention programme Step 1: Watchful waiting for 6 weeks (no intervention offered) Step 2: Cognitive bibliotherapy for 6 weeks Step 3: Individual coping with depression course (12x weekly sessions of 45 mins) Step 4: Indicated treatment (referred to a physician/psychot herapist and treatment could consist of any intervention considered necessary)	Standard care	Duration of programme contact (in months): 12 Outcomes: Relapse at 12 months Antidepressant use at 12 months Discontinuation at 12 months

Study

Population

Intervention

Comparison

Comments

RCT

Netherlands

N=136

Baseline severity: Less severe

Mean age (years): 65.6

Sex (% female): 72

Ethnicity (% BME): NR

Stepped care relapse prevention programme

Step 1: Watchful waiting for 6 weeks (no intervention offered)

Step 2: Cognitive bibliotherapy for 6 weeks

Step 3: Individual coping with depression course (12x weekly sessions of 45 mins)

Step 4: Indicated treatment (referred to a physician/psychot herapist and treatment could consist of any intervention considered necessary)

Standard care

Duration of programme contact (in months): 12

Outcomes:

: BME: black minority ethnic; N: number; NR: not reported; RCT: randomised controlled trial

Service delivery Models and settings for delivery of services: Depression in adults: Evidence review A.

NICE Guideline, No. 222.

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