Kocsis 2009/Klein 2011
RCT
US
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N=395
Mean age (years): 45.8
Gender (% female): 57
Ethnicity (% BME): 10
Baseline severity: HAMD 19.48 (more severe)
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Cognitive behavioral analysis system of psychotherapy (CBASP) + any antidepressant (algorithm-based)
Intensity: 16-20 sessions
| Brief Supportive Psychotherapy + any antidepressant (algorithm-based) | Inadequate response (≥60% reduction in HAMD score, a HAMD total score<8, and no longer meeting DSM-IV criteria for MDD for 2 consecutive visits during weeks 6-12) to 12 weeks of antidepressant medication according to a pharmacotherapy algorithm |
Treatment length (weeks): 12
Outcomes:
Depression symptomatology endpoint Remission Discontinuation due to any reason Discontinuation due to side effects Functional impairment endpoint
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