Table 4.

Recommended Evaluations Following Initial Diagnosis in Individuals with SOST-Related Sclerosing Bone Dysplasia

System/ConcernEvaluation
Skeletal
  • Radiographic & imaging studies incl bone densitometry
  • Assessment of necessity for surgical correction of syndactyly when present
Neurologic Neurologic evaluation for consequences of cranial nerve entrapment
Ophthalmologic Ophthalmologic evaluation for evidence of increased intracranial pressure &/or proptosis
Hearing Formal audiologic evaluation
Other Consultation w/clinical geneticist &/or genetic counselor

From: SOST-Related Sclerosing Bone Dysplasias

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