Table 3, Economic evidence profile of an economic evaluation of the addition of radiotherapy for people undergoing surgery for metastatic spinal cord compression - Evidence reviews for radiotherapy

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Study	Limitations	Applicability	Other comments	Incremental			Uncertainty
Study	Limitations	Applicability	Other comments	Costs	Effect	Cost effectivenss	Uncertainty
Turner 2018 Surgery and radio-therapy versus radio-therapy	Potentially serious limitations¹	Directly applicable²	Radiotherapy arm was based on modelling using values from Patchell 2005	− £12,839	0.32 QALYs	Surgery and radiotherpay dominant³	Various deterministic sensitivity analyses always favoured surgery and radiotherapy

1: Limited exploration of uncertainty.
2: UK NHS perspective with QALYs valued using EQ-5D questionnaire scored using the UK population value set
3: Surgery and radiotherapy both less costly and more effective

Evidence reviews for radiotherapy: Spinal metastases and metastatic spinal cord compression: Evidence review M.

NICE Guideline, No. 234.

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