Table 21Odds ratio, log odds ratio and 95% CrIs for ICU admission for all interventions compared with placebo, vaginal birth subgroup

InterventionNMA OR (95% CrI)NMA LogOR (95% CrI)Number of studies providing direct evidence
Ergometrine0.000 (0.000, 0.692)−25.12 (−70.43, −0.3677)-
Misoprostol plus oxytocin0.262 (0.005, 9.459)−1.339 (−5.293, 2.247)-
Oxytocin >5 IU and ≤ 10 IU0.711 (0.081, 7.721)−0.3406 (−2.518, 2.044)-
Carbetocin0.746 (0.081, 8.542)−0.2936 (−2.513, 2.145)-
Misoprostol ≤ 600 mcg0.950 (0.118, 9.217)−0.05112 (−2.141, 2.221)1
Ergometrine plus oxytocin7.13E+10 (0.925, 9.80E+30)24.99 (−0.07789, 71.36)-

Results from the random effects NMA. OR<1 favours the intervention (lower risk of ICU admission in the intervention arm, with lower numbers indicating a greater effect), OR>1 favours placebo. Abbreviations: OR, odds ratio; CrI, credible interval.

From: Evidence reviews for uterotonics for the prevention of postpartum haemorrhage

Cover of Evidence reviews for uterotonics for the prevention of postpartum haemorrhage
Evidence reviews for uterotonics for the prevention of postpartum haemorrhage: Intrapartum care: Evidence review M.
NICE Guideline, No. 235.
Copyright © NICE 2023.

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