Table 5Median treatment ranks and probability of being the best treatment for all interventions for PPH ≥ 1000mL, vaginal birth subgroup

InterventionMedian (95% CrI) treatment rankProbability of being best
Carboprost2 (1, 11)23.14%
Misoprostol >600 mcg and ≤ 800 mcg2 (0, 12)57.63%
Ergometrine plus oxytocin4 (2, 7)1.10%
Carbetocin5 (2, 9)1.17%
Misoprostol plus oxytocin5 (1, 10)1.39%
Ergometrine4 (1, 11)4.66%
Oxytocin >1 IU and ≤ 5 IU7 (2, 10)0.39%
Oxytocin >5 IU and ≤ 10 IU7 (4, 10)0.00%
Oxytocin ≤1 IU10 (1, 12)9.95%
Misoprostol ≤ 600 mcg9 (6, 11)0.00%
Oxytocin > 10 IU10 (3, 12)0.57%
Placebo11 (10, 12)0.00%

Misoprostol >800 mcg and ≤ 1000 mcg is excluded from the ranking due to highly uncertain estimates.

From: Evidence reviews for uterotonics for the prevention of postpartum haemorrhage

Cover of Evidence reviews for uterotonics for the prevention of postpartum haemorrhage
Evidence reviews for uterotonics for the prevention of postpartum haemorrhage: Intrapartum care: Evidence review M.
NICE Guideline, No. 235.
Copyright © NICE 2023.

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