| Locus* | OMIM | Map Position | Gene | Inheritance | Pathology | Ref. |
|---|---|---|---|---|---|---|
| PARK1 | #168601 | 4q21-q23 | α-syncluein | dominant, high penetrance | LB+ | 54 |
| PARK2 | #600116 | 6q25-q27 | parkin | recessive | mostly LB negative | 55 |
| PARK3 | 602604 | 2p13 | unknown | dominant-incomplete penetrance | LB+ | 53 |
| PARK4 | 605543 | 4p15 | unknown | dominant, high penetrance | LB+ | 56 |
| PARK5 | 191342 | 4p14 | UCH-L1 | dominant | unknown | 57 |
| PARK6 | 605909 | 1p35-p36 | unknown | recessive | unknown | 4 |
| PARK7 | #606324 | 1p36 | DJ-1 | recessive | unknown | 9 |
| PARK8 | 607060 | 12p11-q13 | unknown | dominant, incomplete penetrance | LB negative | 33 |
| PARK9 | pending | 1p36 | unknown | recessive | unknown | 6 |
| PARK10 | 606852 | 1p32 | unknown | non-Mendelian | unknown | 7 |
| pending | 601828 | 2q22-q23 | NR4A2(NURR1) | dominant(?) | unknown | 52 |
| pending | pending | 2q36-q37 | unknown | non-mendelian | unknown | 42 |
* Named according to HUGO Gene Nomenclature Committee (http://www.gene.ucl.ac.uk/nomenclature).
From: Chromosome 1 and Other Hotspots for Parkinson's Disease Genes
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.