Table 2, Effects of mutations in the identity elements of Eco-tRNATyr on charging by Eco-TyrRSa - Madame Curie Bioscience Database

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Mutation	K_M(tRNA^Try)	K_cat	K_cat/K_M
Native	0.75	1.03	1.40
wt(transcript)	1.00	1.00	1.00
G34C	1.64	0.068	0.043
U35G	15.6	0.076	0.0048
Δ(U46,U47)^b	10.0	0.31	0.031
∑(A44.1,A44.2)^b	na^c	na	0.0031
A73G	2.84	0.076	0.027
A73C	3.44	0.45	0.13
A73U	4.06	0.26	0.064

: ^a Relative values.⁵¹^,⁵² The double mutation (G1C, C72G) also decreases the rate of aminoacylation.⁵³
: ^b Δ, deletion; ∑, insertion.
: ^c na, not available.

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