Table 5Recognition of the identity nucleotides of tRNATyr by Bst-TyrRS and Tth-TyrRS19,26,29

NucleotideGroupBst-TyrRSTth-TyrRS
A73N6-H2 Ala150, mcC=0a Glu154, mcC=0
A73N1 Lys151
A73C2-HTrp196, Cδ1-H
A73N3 Trp196, Cδ1-HArg198
G1baseTrp196, packingLeu202,packing
G1N3 Arg198
C72N4 Glu154
C71N4 Glu154
G34N1-N2 Asp259
Psi35N3 Asp423Glu154, mcC=0
Psi35N1 Tyr342, mcC=0
Psi35basePhe323,aromaticb Tyr342, aromatic

a mc, main-chain.

b Although Phe323 in Bst-TyrRS aligns with Ala346 in Tth-TyrRS, it could play a role similar to that of Tyr342 in Tth-TyrRS.

From: Tyrosyl-tRNA Synthetases

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