Table 2. Risk Assessment of Nongastric GISTs by Tumor Size and Mitotic Indexa

Mitotic Index (mitoses/HPF)Size (cm)Metastasis Rate (%)Risk of Progressive Disease
≤5 per 50 ≤2 0None
>2 to ≤5 1.9–8.5Low
>5 to ≤10 24Insufficient data–Moderate
>1034–52High
>5 per 50 ≤250–54Insufficient data–High
>2 to ≤5 50–73High
>5 to ≤10 85High
>1071–90High

GISTs = gastrointestinal stromal tumors; HPF = high-power field.

aAdapted from Miettinen et al.[25] and Laurini et al.[33]

From: Gastrointestinal Stromal Tumors Treatment (PDQ®)

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PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.

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