From: Childhood Non-Hodgkin Lymphoma Treatment (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 6. Variant ALK Translocation and Associated Partner Chromosome Location and Frequencya
| Gene Fusion | Partner Chromosome Location | Frequency of Gene Fusion |
|---|---|---|
| NPM-ALK | 5q36.1 | Approximately 80% |
| TPM3-ALK | 1p23 | Approximately 15% |
| ALO17-ALK | 17q25.3 | Rare |
| ATIC-ALK | 2q35 | Rare |
| CLTC-ALK | 17q23 | Rare |
| MSN-ALK | Xp11.1 | Rare |
| MYH9-ALK | 22q13.1 | Rare |
| TFG-ALK | 3q12.2 | Rare |
| TPM4-ALK | 19p13 | Rare |
| TRAF1-ALK | 9q33.2 | Rare |
aAdapted from Tsuyama et al.[7]