From: Childhood Non-Hodgkin Lymphoma Treatment (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 6. Variant ALK Translocation and Associated Partner Chromosome Location and Frequencya
| Gene Fusion | Partner Chromosome Location | Frequency of Gene Fusion |
|---|---|---|
| NPM::ALK | 5q36.1 | Approximately 80% |
| TPM3::ALK | 1p23 | Approximately 15% |
| ALO17::ALK | 17q25.3 | Rare |
| ATIC::ALK | 2q35 | Rare |
| CLTC::ALK | 17q23 | Rare |
| MSN::ALK | Xp11.1 | Rare |
| MYH9::ALK | 22q13.1 | Rare |
| TFG::ALK | 3q12.2 | Rare |
| TPM4::ALK | 19p13 | Rare |
| TRAF1::ALK | 9q33.2 | Rare |
aAdapted from Tsuyama et al.[8]